Acknowledgements

Thanks to Mr. Tor-Arne Vilnes for expert help with preparing the text and the figures.

This study was supported in part by the Research Council of Norway.

References

Agati G and Fusi F. New trends in photobiology (invited review). Recent advances in bilirubin photophysics. J. Photochem.Photobiol.B: Biol. 1990; 7: 1-14

Amundsen I. Optimalisering og dosimetri ved lysbehandling av nyfødte med hyperbilirubinemi. SIS-rapport 1991:7, Østerås, Statens strålevern (in Norwegian)

Böhm F, Drygalla F, Charlesworth A, Böhm K, Truscott TG and Jokiel K. Bilirubin phototoxicity to human cells by green light phototherapy in vitro . Photochem. Photobiol. 1995; 62: 980-983

Christensen T. Photosensitization of human cells by bilirubin (abstract). Photochem. Photobiol. 1984; 39, Suppl. p 39

Christensen T. Cytotoxicity of bilirubin photptoducts. Photobiochemistry and Photobiophysics. 1986; 10, 253-260.

Christensen T, Støttum A, Brunborg G and Reitan JB. Unwanted side effects and optimization of phototherapy. In: R.H.Douglas, J.Moan, F.Dall'Acqa (Eds.). Light in biology and medicine, Vol I. Plenum Press, (1988): 153 - 159.

Christensen T, Reitan JB and Kinn G. Single-strand breaks in the DNA of human cells exposed to visible light from phototherapy lamps in the presence and absence of bilirubin. J. Photochem. Photobiol. B. Biol. 1990; 7:337-346.

Christensen T, Kinn G, Granli T and Amundsen I. Cells, bilirubin and light: Formation of bilirubin photoproducts and cellular damage at defined wavelengths. Acta Pædiatr. 1994; 83: 7-12

Christensen T, Kinn G, Granli T and Amundsen I. Bilirubin and light effects on cells. 12th International Congress on photobiology, 1996, Book of abstracts: O46, p. 208

Cremer RJ, Perryman PW and Richards DH. Influence of light on the hyperbilirubinaemia of infants. Lancet 1958; 1: 1094-1097

[Up]

Deziel MR and Girotti AW. Photodynamic action of bilirubin on liposomes and erythrocyte membranes. J. Biol. Chem. 1980; 255: 8192-8198

Ennever JF and Dresing TJ. Quantum yields for the cyclization and configurational isomerization of 4E,15Z-bilirubin. J. Photochem. Photobiol. 1991; 53:25-32.

Girotti AW. Photodynamic action of bilirubin on human erythrocyte membranes. Modification of polypeptide constituents. Biochem. 1975; 14: 3377-3383

Girotti AW. Bilirubin sensitized photoinactivation of enzymes in the isolated membrane of the human erythrocyte. Photochem. Photobiol 1976; 24: 525-532

Girotti AW. Bilirubin-photosensitized cross-linking of polypeptides in the isolated membrane of the human erythrocyte. J. Biol. Chem. 1978; 253: 7186-7193

Fischer H and Herle K. Einwirkung von Licht auf Porphyrine. Überfürung von Ätio-porphyrin I in bilirubinoid Farbstoffe. Hoppe Zeyler Z. Physiol. Chem 1938; 251: 85-96

Kessel D, Luo Y, Deng Y and Chang CK . The role of subcellular localization in initiation of apoptosis by photodynamic therapy. Photochem Photobiol 1997; 65: 422-426

Knobloch E, Mandys F, Hodr R, Hujer R and Mader R. Study of the mechanism of the photoisomerisation and photooxidation of bilirubin using a model for the phototherapy of hyperbilirubinemia. J. Chromatogr. 1991; 566: 89-99

Landen GL, Park Y-T and Lightner DA. On the role of singlet oxygen in the self-sensitized photo-oxygenation of bilirubin and its pyrromethenone models. Tetrahedron 1982; 39: 1893-1907

Matheson IBC. The absolute value of the reaction rate constant of bilirubin with singlet oxygen in D₂O. Photochem. Photobiol. 1979; 29: 875-878

[Up]

McDonagh AF, Agati G, Fusi F and Pratesi R. Quantum yields for laser photocyclization of bilirubin in the presence of human serum albumin. Dependence of quantum yield on excitation wavelength. Photochem. Photobiol. 1989; 50:305-319.

McDonagh, AF. The role of oxygen in bilirubin photo-oxidation. Biochem. Biophys. Res. Comm. 1971; 44: 1306-1311

McDonagh AF, Lightner DA and Wooldridge TA. Geometric isomerisation of bilirubin IXa and its dimethyl ester. JCS Chem. Comm. 1979; 1029:110-112

Meisel P, Jährig D and Jährig K. Kinetics of self-sensitized and riboflavin-sensitized photodegradation of bilirubin. Acta Biol. Med. Germ. 1980; 39: 763-770

Rosenstein BS, Ducore JM and Cummings SW. The mechanism of bilirubin-photosensitized DNA strand breakage in human cells exposed to phototherapy light. Mutation Research 1983; 112: 397-406.

Sloper RW and Truscott TG. The quantum yield for bilirubin photoisomerisation. Photochem. Photobiol 1982; 35: 743-745

Troup GJ, Agati G, Fusi F and Pratesi R. On the variable quantum yield of asymmetric bilirubin. Austr. J. Phys. 1996; 49: 673-681

Yuspa SH and Morgan D. Mouse skin cell resistant to terminal differentiation associated with initiation of carcinogenesis. Nature 1981; 293:72-74.

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